
IFN alpha-IFNAR-IN-1 hydrochloride
CAS No. 2070014-98-9
IFN alpha-IFNAR-IN-1 hydrochloride ( —— )
产品货号. M26256 CAS No. 2070014-98-9
IFN α-IFNAR-IN-1 saltchide 是 IFN-α 和 IFNAR 之间相互作用的抑制剂。 IFN α-IFNAR-IN-1 saltchide 抑制 BM-pDCs 诱导的 MVA IFN-α 反应,IC50 为 2-8 μM。
纯度: >98% (HPLC)






规格 | 价格/人民币 | 库存 | 数量 |
2MG | ¥478 | 有现货 |
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5MG | ¥778 | 有现货 |
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10MG | ¥1045 | 有现货 |
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25MG | ¥1806 | 有现货 |
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50MG | ¥2827 | 有现货 |
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100MG | ¥4228 | 有现货 |
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200MG | 获取报价 | 有现货 |
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500MG | 获取报价 | 有现货 |
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1G | 获取报价 | 有现货 |
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生物学信息
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产品名称IFN alpha-IFNAR-IN-1 hydrochloride
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述IFN α-IFNAR-IN-1 saltchide 是 IFN-α 和 IFNAR 之间相互作用的抑制剂。 IFN α-IFNAR-IN-1 saltchide 抑制 BM-pDCs 诱导的 MVA IFN-α 反应,IC50 为 2-8 μM。
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产品描述IFN alpha-IFNAR-IN-1 hydrochloride is an inhibitor of the interaction between IFN-α and IFNAR. IFN alpha-IFNAR-IN-1 hydrochloride inhibits MVA-induced IFN-α responses by BM-pDCs with IC50 of 2-8 μM.(In Vitro):IFN alpha-IFNAR-IN-1 hydrochloride inhibited the IFN-α responses that were elicited after treatment with CpG2216, stimulation with poly(I:C), and infection with VSV-M2, whereas the total IL-12 production was notably less affected under those conditions. IFN alpha-IFNAR-IN-1 hydrochloride specifically inhibits MVA-induced IFN-α responses by BM-pDCs. IFN alpha-IFNAR-IN-1 hydrochloride exerts immunosuppressive activity by the direct interaction with IFN-α.
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体外实验IFN alpha-IFNAR-IN-1 (compound 1) (18 μM; 24 h) specifically inhibits MVA-induced IFN-a responses by BMpDCs.
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体内实验——
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同义词——
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通路Others
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靶点Other Targets
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受体antimalarial
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研究领域——
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适应症——
化学信息
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CAS Number2070014-98-9
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分子量315.86
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分子式C18H18ClNS
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO : 100 mg/mL (316.60 mM)
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SMILESCl.CNCc1ccccc1Sc1cccc2ccccc12
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Marcsisin SR, et al. Tafenoquine and NPC-1161B require CYP 2D metabolism for anti-malarial activity: implications for the 8-aminoquinoline class of anti-malarial compounds. Malar J. 2014 Jan 3;13:2.
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